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We are an interdisciplinary group interested in super-resolution live-cell imaging, adaptation to stress, and drug resistance biology in pathogens
A bit about our research The focus of our group is on the mechanisms of cellular adaptations to stress and aging, in particular those involving dynamic sweeping rearrangements in cellular architecture . Adaptation enables certain pathogenic microorganisms to withstand severe stress and acquire drug resistance. Cancer progression is also dependent on cellular remodeling. The overall goal of our lab is to develop a full mechanistic understanding of adaptation in fungi and mammalian cells. To this end we apply a diverse set of tools from biochemistry, to yeast genetics, mammalian cell biology, drug screens, and simple model organisms. |
School of Biological Sciences Life Sciences Building (building 85), Highfield Campus, Southampton SO17 1BJ University of Southampton |