Project Title: Harnessing the Dark Side of Protein Folding: Manipulating Aggregation for Recombinant Protein Production. Award Amount: $2,500,000 Duration of Award: October 2013 - September 2019
Joint Project: Simon Alberti (PI), Serena Carra, Angelo Poletti, Nico Dantuma, Jared Sterneckert Project Title: Stress granules and proteostasis in motor neurons: towards a mechanistic understanding of ALS. Award Amount: $2,011,698 Duration of Award: January 2016 - December 2019
Project Title: Dynamics and function of stress granules and other protein-RNA assemblies in Amyotrophic Lateral Sclerosis. Joint Project: Serena Carra, University of Modena Award Amount: $200,000 Duration of Award: October 2016 - September 2018
Joint Project: Subramaniam Ganesh and Pratibha Siwach Project Title: Deciphering the structural role of glycogen in neuronal autophagy and neurodegeneration. Award Amount: $320,000 Duration of Award: October 2016 - September 2019
Project Title: The neuronal cell biology of Tauopathy: examining the etiology of neuron-specific toxicity of Tau aggregation. Award Amount: $45,000 Duration of Award: August 2015 - July 2017
Project Title: Building a molecular map of alpha-synuclein toxicity. Joint Project: Tiago Outeiro and Silvio Rizzoli from the University of Goettingen Award Amount: $182,400 Duration of Award: January 2014 - December 2016
Niedersachsen-Israel Research Cooperation Program Project Title: The role of membrane binding on alpha-synuclein aggregation and cell-to-cell propagation in models of Parkinson’s Disease. Joint Project: Tiago Outeiro from the University of Goettingen Award Amount: $300,000 Duration of Award: January 2014 - June 2017
Project Title: Towards the Understanding of Pathological Protein Processing and Toxicity in Machado-Joseph Disease. Joint Project: Philipp Koch, Dineke Verbeek, Luis Pereira de Almeida, and Thorsten Schmidt Award Amount: $1,200,000 Duration of Award: January 2013 - December 2015
Project Title: The Cell Biology of Protein Aggregation in a C. elegans Alzheimer Model. Award Amount: $100,000 Duration of Award: July 2012 - June 2014
Project Title: Amyloid management in yeast through spatial organization of aggregated proteins in the cytosol. Award Amount: $45,000 Duration of Award: August 2011 - July 2013
Project Title:Determine the
basis for the neuronal cell-type specificity of aggregation-induced toxicity:
Examining the effect of neural stimulation and activity on protein folding
stress and oxidative stress tolerance in neurons. Award Amount: $25,000 Duration of Award: October 2011 - September 2012
